1:30 PM Welcome Remarks
1:40 PM Jaewon Min, Assistant Professor of Pathology and Cell Biology, Columbia University
Distinct Mechanisms of C- and G-circle Generation in Human ALT Cancers
2:10 PM Shan Zha, James A Wolff Professor, Columbia University
Exaptation: Understanding the Essential Function of KU in Human Cells
2:40 PM Tzippora Chwat-Edelstein, student, MSKCC
Optimal RPA affinity toward ssDNA preferentially affects R-loop homeostasis and cellular resistance to topological stress
2:55 PM coffee break
3:15 PM Zack Zheng, student, MSKCC
Reconstitution of SPO11-catalyzed double-strand-breaks
3:30 PM Karen Schindler, Professor, Rutgers University
Unraveling the functions of Sirtuin 7 during oocyte aging
4:00 PM John Maciejowski, Member, Molecular Biology Program, MSKCC
Mechanisms of APOBEC3 mutagenesis
4:30-5:30 PM Reception